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Why Is Too Much Vitamin B6 Causing Neuropathy — Energy Drinks + Supplement Overload

  • johnhayesjr1
  • Jul 21
  • 2 min read

Why Is Too Much Vitamin B6 Is Causing Neuropathy? Vitamin B6 (pyridoxine) is crucial for amino acid metabolism, neurotransmitter synthesis, and energy production. Adults need only about 1.3–2 mg of vitamin B6 per day, with tolerable upper limits ranging from 12–100 mg/day depending on the agency. However, excessive intake—often from supplements or fortified beverages—can lead to peripheral neuropathy: tingling, numbness, and nerve pain in the hands and feet.

🚨 Rising Cases from Vitamin B6 Over‑Supplementation & References

Recent reports highlight a surge in neuropathy related to high B6 consumption:

  • Australia’s TGA received 119–174 reports since 2020 and is tightening regulations, limiting over‑the‑counter doses to under 50 mg/day and requiring pharmacist consultation PMC+12ABC+12Daily Telegraph+12.

  • In one case, a man taking combined multivitamin and magnesium supplements had B6 levels 36× normal—and nerve pain that only improved after stopping supplements PMC+15The Guardian+15Brain Foundation+15.

  • Studies show neuropathy developing even at lower doses over prolonged use—sometimes below 50 mg/day—especially when stacked from multiple products Therapeutic Goods Administration (TGA)HSA.

Energy Drinks + Vitamin B6 Supplement Overload

Energy drinks often contain 2–40 mg of B6 per serving Nature+1AAAN+1. In one series, seven cases described neuropathic pain in energy drink consumers; symptoms improved after quitting Medical Republic+3AAAN+3PMC+3. Combined with multivitamins, it’s easy to exceed safe levels unwittingly.

What You Can Do

  1. Check labels—learn your total B6 intake, including from energy drinks and supplements.

  2. Limit The Dosage, not megadoses; avoid supplements providing more than 25mg unless prescribed by a Physician.

    Why Is Too Much Vitamin B6 Is Causing Neuropathy?
    Why Is Too Much Vitamin B6 Is Causing Neuropathy? Vitamin B6
  3. Stop if you feel symptoms—tingling, numbness, or muscle weakness should trigger a Comprehensive Evaluation. Be sure to see your physician!


In summary: vitamin B6 is essential but toxic in excess. Whether via energy drinks, multivitamins, or combined sources, unchecked intake can damage peripheral nerves. Awareness, moderation, and medical guidance are key to staying safe.




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